2KUO

Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response

Summary for 2KUO

• Entry DOI: 10.2210/pdb2kuo/pdb
• NMR Information: BMRB: 16744
• Descriptor: Aprataxin and PNK-like factor, ZINC ION (2 entities in total)
• Functional Keywords: aprataxin pnk-like factor (aplf), poly adp-ribose (par), par-binding zinc finger (pbz), dna damage, adp-ribose, adp-ribosylation, dna repair, metal-binding, nucleotide-binding, nucleus, zinc, zinc-finger, metal binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q8IW19
• Total number of polymer chains: 1
• Total formula weight: 10403.14

Authors

Li, G.Y.,McCulloch, R.D.,Fenton, A.,Cheung, M.,Meng, L.,Ikura, M.,Koch, C.A. (deposition date: 2010-02-23, release date: 2010-05-05, Last modification date: 2022-03-16)

• Primary citation: Li, G.Y.,McCulloch, R.D.,Fenton, A.,Cheung, M.,Meng, L.,Ikura, M.,Koch, C.A.; Structure and identification of ADP-ribose recognition motifs of aprataxin PNK-like factor (APLF) required for the interaction with sites of DNA damage response; To be Published,

Experimental method

SOLUTION NMR