2KU7

Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein

Summary for 2KU7

Entry DOI	10.2210/pdb2ku7/pdb
Descriptor	MLL1 PHD3-Cyp33 RRM chimeric protein (1 entity in total)
Functional Keywords	mll1, cyp33, transcriptional regulation, rrm domain, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q9UNP9
Total number of polymer chains	1
Total formula weight	15257.95
Authors	Song, J.,Wang, Z.,Patel, D. (deposition date: 2010-02-12, release date: 2010-07-07, Last modification date: 2022-03-16)
Primary citation	Wang, Z.,Song, J.,Milne, T.A.,Wang, G.G.,Li, H.,Allis, C.D.,Patel, D.J. Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141:1183-1194, 2010 Cited by PubMed: 20541251 DOI: 10.1016/j.cell.2010.05.016 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation