2KRI

Structure of a complex between domain V of beta2-glycoprotein I and the fourth ligand-binding module from LDLR determined with Haddock

Summary for 2KRI

• Entry DOI: 10.2210/pdb2kri/pdb
• NMR Information: BMRB: 16639
• Descriptor: Beta-2-glycoprotein 1, Low-density lipoprotein receptor, CALCIUM ION (3 entities in total)
• Functional Keywords: antiphospholipid syndrome, thrombosis, ldlr, receptor, disulfide bond, glycoprotein, heparin-binding, sushi, protein binding-endocytosis complex, protein binding/endocytosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 14017.92

Authors

Beglova, N. (deposition date: 2009-12-18, release date: 2010-03-31, Last modification date: 2019-11-06)

• Primary citation: Lee, C.J.,De Biasio, A.,Beglova, N.; Mode of interaction between beta2GPI and lipoprotein receptors suggests mutually exclusive binding of beta2GPI to the receptors and anionic phospholipids.; Structure, 18:366-376, 2010; PubMed: 20223219; DOI: 10.1016/j.str.2009.12.013

Experimental method

SOLUTION NMR