2KNY
Fusion construct of CR17 from LRP-1 and ApoE residues 130-149
Summary for 2KNY
Entry DOI | 10.2210/pdb2kny/pdb |
NMR Information | BMRB: 16483 |
Descriptor | LRP-1, linker, Apo-E, CALCIUM ION (2 entities in total) |
Functional Keywords | lrp, apoe, lipoprotein receptor, ligand binding module, complement repeat, calcium, cell membrane, coated pit, cytoplasm, developmental protein, disulfide bond, egf-like domain, endocytosis, glycoprotein, membrane, metal-binding, nucleus, phosphoprotein, polymorphism, receptor, transmembrane, protein binding, metal binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 8439.51 |
Authors | Guttman, M.,Komives, E.A. (deposition date: 2009-09-08, release date: 2010-04-14, Last modification date: 2020-02-26) |
Primary citation | Guttman, M.,Prieto, J.H.,Handel, T.M.,Domaille, P.J.,Komives, E.A. Structure of the minimal interface between ApoE and LRP. J.Mol.Biol., 398:306-319, 2010 Cited by PubMed: 20303980DOI: 10.1016/j.jmb.2010.03.022 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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