2KN7

Structure of the XPF-single strand DNA complex

Summary for 2KN7

• Entry DOI: 10.2210/pdb2kn7/pdb
• Related: 1z00 2aq0
• NMR Information: BMRB: 16449
• Descriptor: DNA repair endonuclease XPF, DNA (5'-D(*CP*AP*GP*TP*GP*GP*CP*TP*GP*A)-3') (2 entities in total)
• Functional Keywords: ner, xpf/ercc1, hhh, protein-ssdna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Probable): Q92889
• Total number of polymer chains: 4
• Total formula weight: 21016.94

Authors

Das, D.,Folkers, G.E.,van Dijk, M.,Jaspers, N.G.J.,Hoeijmakers, J.H.J.,Kaptein, R.,Boelens, R. (deposition date: 2009-08-16, release date: 2010-08-04, Last modification date: 2012-07-04)

• Primary citation: Das, D.,Folkers, G.E.,van Dijk, M.,Jaspers, N.G.J.,Hoeijmakers, J.H.J.,Kaptein, R.,Boelens, R.; The structure of the XPF-ssDNA complex underscores the distinct roles of the XPF and ERCC1 helix- hairpin-helix domains in ss/ds DNA recognition; Structure, 20:667-675, 2012; PubMed: 22483113; DOI: 10.1016/j.str.2012.02.009

Experimental method

SOLUTION NMR