2KKG
NMR structure of the octarepeat region of prion protein bound to pentosan polysulfate
Summary for 2KKG
| Entry DOI | 10.2210/pdb2kkg/pdb |
| NMR Information | BMRB: 16505 |
| Descriptor | Major prion protein (1 entity in total) |
| Functional Keywords | prion protein, octapeptide repeats, pentosan polysulfate, sulfated glycans, cell membrane, disulfide bond, glycoprotein, golgi apparatus, gpi-anchor, lipoprotein, membrane, prion, membrane protein |
| Biological source | Mesocricetus auratus (golden hamsters) |
| Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04273 |
| Total number of polymer chains | 1 |
| Total formula weight | 8696.39 |
| Authors | Taubner, L.M.,Caughey, B.,Copie, V. (deposition date: 2009-06-19, release date: 2009-11-10, Last modification date: 2022-03-16) |
| Primary citation | Taubner, L.M.,Bienkiewicz, E.A.,Copie, V.,Caughey, B. Structure of the flexible amino-terminal domain of prion protein bound to a sulfated glycan. J.Mol.Biol., 395:475-490, 2010 Cited by PubMed: 19913031DOI: 10.1016/j.jmb.2009.10.075 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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