2KES
Solution Structure of the Coiled-coil Domain of Synphilin-1
Summary for 2KES
Entry DOI | 10.2210/pdb2kes/pdb |
NMR Information | BMRB: 16156 |
Descriptor | Synphilin-1 (1 entity in total) |
Functional Keywords | synphillin, coiled-coil, ank repeat, disease mutation, parkinson disease, phosphoprotein, polymorphism, ubl conjugation, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9Y6H5 |
Total number of polymer chains | 1 |
Total formula weight | 5371.14 |
Authors | Xie, Y.Y.,Zhou, C.J.,Zhou, Z.R.,Hu, H.Y. (deposition date: 2009-02-02, release date: 2009-02-24, Last modification date: 2022-03-16) |
Primary citation | Xie, Y.Y.,Zhou, C.J.,Zhou, Z.R.,Hong, J.,Che, M.X.,Fu, Q.S.,Song, A.X.,Lin, D.H.,Hu, H.Y. Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication. Faseb J., 24:196-205, 2010 Cited by PubMed: 19762560DOI: 10.1096/fj.09-133082 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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