2KE1
Molecular Basis of non-modified histone H3 tail Recognition by the First PHD Finger of Autoimmune Regulator
Summary for 2KE1
Entry DOI | 10.2210/pdb2ke1/pdb |
Related | 1XWH |
NMR Information | BMRB: 16510 |
Descriptor | Autoimmune regulator, H3K4me0, ZINC ION (3 entities in total) |
Functional Keywords | aire, phd finger, histone h3, disease mutation, metal-binding, nucleus, transcription, transcription regulation, zinc, zinc-finger, gene regulation |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: O43918 |
Total number of polymer chains | 2 |
Total formula weight | 8426.25 |
Authors | Chignola, F.,Gaetani, M.,Rebane, A.,Org, T.,Mollica, L.,Zucchelli, C.,Spitaleri, A.,Mannella, V.,Peterson, P.,Musco, G. (deposition date: 2009-01-22, release date: 2009-05-26, Last modification date: 2022-03-16) |
Primary citation | Chignola, F.,Gaetani, M.,Rebane, A.,Org, T.,Mollica, L.,Zucchelli, C.,Spitaleri, A.,Mannella, V.,Peterson, P.,Musco, G. The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation Nucleic Acids Res., 37:2951-2961, 2009 Cited by PubMed: 19293276DOI: 10.1093/nar/gkp166 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report