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2KE1

Molecular Basis of non-modified histone H3 tail Recognition by the First PHD Finger of Autoimmune Regulator

Summary for 2KE1
Entry DOI10.2210/pdb2ke1/pdb
Related1XWH
NMR InformationBMRB: 16510
DescriptorAutoimmune regulator, H3K4me0, ZINC ION (3 entities in total)
Functional Keywordsaire, phd finger, histone h3, disease mutation, metal-binding, nucleus, transcription, transcription regulation, zinc, zinc-finger, gene regulation
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus: O43918
Total number of polymer chains2
Total formula weight8426.25
Authors
Chignola, F.,Gaetani, M.,Rebane, A.,Org, T.,Mollica, L.,Zucchelli, C.,Spitaleri, A.,Mannella, V.,Peterson, P.,Musco, G. (deposition date: 2009-01-22, release date: 2009-05-26, Last modification date: 2022-03-16)
Primary citationChignola, F.,Gaetani, M.,Rebane, A.,Org, T.,Mollica, L.,Zucchelli, C.,Spitaleri, A.,Mannella, V.,Peterson, P.,Musco, G.
The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation
Nucleic Acids Res., 37:2951-2961, 2009
Cited by
PubMed: 19293276
DOI: 10.1093/nar/gkp166
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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