2K60

NMR structure of calcium-loaded STIM1 EF-SAM

Summary for 2K60

• Entry DOI: 10.2210/pdb2k60/pdb
• NMR Information: BMRB: 15851
• Descriptor: PROTEIN (Stromal interaction molecule 1), CALCIUM ION (2 entities in total)
• Functional Keywords: ef-hand, sam domain, ef-sam, stim1, stromal interaction molecule, store operated calcium entry regulator, soce, endoplasmic reticulum luminal calcium sensor, calcium transport, glycoprotein, ion transport, membrane, phosphoprotein, transmembrane, transport, transport protein, signaling protein
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane; Single-pass type I membrane protein: Q13586
• Total number of polymer chains: 1
• Total formula weight: 17420.45

Authors

Stathopulos, P.B.,Ikura, M. (deposition date: 2008-07-02, release date: 2008-10-07, Last modification date: 2013-07-24)

• Primary citation: Stathopulos, P.B.,Zheng, L.,Li, G.Y.,Plevin, M.J.,Ikura, M.; Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.; Cell(Cambridge,Mass.), 135:110-122, 2008; PubMed: 18854159; DOI: 10.1016/j.cell.2008.08.006

Experimental method

SOLUTION NMR