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2K4A

FGF-1-C2A binary complex structure: a key component in the fibroblast growthfactor non-classical pathway

Summary for 2K4A
Entry DOI10.2210/pdb2k4a/pdb
Related2K43 2K45
DescriptorSynaptotagmin-1, Heparin-binding growth factor 1 (2 entities in total)
Functional Keywordsbeta barrel, fgf1-c2a binary complex, calcium, cell junction, cytoplasmic vesicle, glycoprotein, lipoprotein, membrane, metal-binding, palmitate, phosphoprotein, synapse, transmembrane, acetylation, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, protein transport
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21579
Secreted: P05230
Total number of polymer chains2
Total formula weight29901.93
Authors
Yu, C.,Mohan, S.K. (deposition date: 2008-06-02, release date: 2009-06-09, Last modification date: 2024-05-29)
Primary citationMohan, S.K.,Yu, C.
FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published,
Experimental method
SOLUTION NMR
Structure validation

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