2JG8
Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine
Summary for 2JG8
Entry DOI | 10.2210/pdb2jg8/pdb |
Related | 1PK6 2JG9 |
Descriptor | Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, ... (7 entities in total) |
Functional Keywords | polymorphism, glycoprotein, phagocytosis, disease mutation, complement pathway, immune system, cell surface molecule, pyrrolidone carboxylic acid, hydroxylation, innate immunity, immune response, collagen, tolerance, apopotosis, complement |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 90374.15 |
Authors | Paidassi, H.,Tacnet-Delorme, P.,Garlatti, V.,Darnault, C.,Ghebrehiwet, B.,Gaboriaud, C.,Arlaud, G.J.,Frachet, P. (deposition date: 2007-02-09, release date: 2008-02-19, Last modification date: 2023-12-13) |
Primary citation | Paidassi, H.,Tacnet-Delorme, P.,Garlatti, V.,Darnault, C.,Ghebrehiwet, B.,Gaboriaud, C.,Arlaud, G.J.,Frachet, P. C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180:2329-2338, 2008 Cited by PubMed: 18250442DOI: 10.4049/jimmunol.180.4.2329 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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