2JG0

Family 37 trehalase from Escherichia coli in complex with 1- thiatrehazolin

Summary for 2JG0

• Entry DOI: 10.2210/pdb2jg0/pdb
• Related: 2JF4
• Descriptor: PERIPLASMIC TREHALASE, N-[(3aS,4R,5S,6S,6aS)-4,5,6-trihydroxy-4-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]thiazol-2-yl]-alpha- D-glucopyranosylamine (3 entities in total)
• Functional Keywords: family 37, hydrolase, inhibitor, trehalase, glycoside hydrolase, periplasmic, glycosidase, 1-thiatrehazolin
• Biological source: ESCHERICHIA COLI
• Cellular location: Periplasm: P13482
• Total number of polymer chains: 1
• Total formula weight: 60908.92

Authors

Gibson, R.P.,Gloster, T.M.,Roberts, S.,Warren, R.A.J.,Storch De Gracia, I.,Garcia, A.,Chiara, J.L.,Davies, G.J. (deposition date: 2007-02-07, release date: 2007-02-13, Last modification date: 2024-10-23)

• Primary citation: Gibson, R.P.,Gloster, T.M.,Roberts, S.,Warren, R.A.J.,Storch De Gracia, I.,Garcia, A.,Chiara, J.L.,Davies, G.J.; Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors.; Angew.Chem.Int.Ed.Engl., 46:4115-, 2007; PubMed: 17455176; DOI: 10.1002/ANIE.200604825

Experimental method

X-RAY DIFFRACTION (1.5 Å)