2J7L

E. coli P Pilus chaperone PapD in complex with a pilus biogenesis inhibitor, pilicide 2c

Summary for 2J7L

Entry DOI	10.2210/pdb2j7l/pdb
Related	1N0L 1PDK 1QPP 1QPX 2J2Z 3DPA
Descriptor	CHAPERONE PROTEIN PAPD, (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID (3 entities in total)
Functional Keywords	fimbria, inhibitor, chaperone, periplasmic, immunoglobulin domain, chaperone/surface active protein, chaperone-surface active protein complex
Biological source	ESCHERICHIA COLI
Cellular location	Periplasm: P15319
Total number of polymer chains	1
Total formula weight	25052.46
Authors	Remaut, H.,Pinkner, J.S.,Hultgren, S.J.,Almqvist, F.,Waksman, G. (deposition date: 2006-10-12, release date: 2006-11-01, Last modification date: 2023-12-13)
Primary citation	Pinkner, J.S.,Remaut, H.,Buelens, F.,Miller, E.,Aberg, V.,Pemberton, N.,Hedenstrom, M.,Larsson, A.,Seed, P.,Waksman, G.,Hultgren, S.J.,Almqvist, F. Rationally Designed Small Compounds Inhibit Pilus Biogenesis in Uropathogenic Bacteria. Proc.Natl.Acad.Sci.USA, 103:17897-, 2006 Cited by PubMed: 17098869 DOI: 10.1073/PNAS.0606795103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation