2J6O

ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETEROTRIMER

Summary for 2J6O

Entry DOI	10.2210/pdb2j6o/pdb
Related	1CDB 1GYA 1HNF 1L2Z 2BZ8 2J6F 2J6K 2J7I
Descriptor	CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2 (3 entities in total)
Functional Keywords	phosphorylation, adaptor protein, egfr downregulation, cms, sh3 domain, sh3-binding, coiled coil, sh3 domain recognition, signaling protein, protein binding
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm, cytoskeleton : Q9Y5K6 Membrane; Single-pass type I membrane protein: P06729
Total number of polymer chains	2
Total formula weight	8531.67
Authors	Moncalian, G.,Cardenes, N.,Deribe, Y.L.,Spinola-Amilibia, M.,Dikic, I.,Bravo, J. (deposition date: 2006-10-02, release date: 2006-10-11, Last modification date: 2017-07-05)
Primary citation	Moncalian, G.,Cardenes, N.,Deribe, Y.L.,Spinola-Amilibia, M.,Dikic, I.,Bravo, J. Atypical Polyproline Recognition by the Cms N-Terminal SH3 Domain. J.Biol.Chem., 281:38845-, 2006 Cited by PubMed: 17020880 DOI: 10.1074/JBC.M606411200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation