2IYO
Structural characterization of a bacterial 6PDH reveals aspects of specificity, mechanism and mode of inhibition
Summary for 2IYO
Entry DOI | 10.2210/pdb2iyo/pdb |
Related | 2IYP 2IZ0 2IZ1 |
Descriptor | 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, CACODYLATE ION, ... (4 entities in total) |
Functional Keywords | oxidoreductase, 6-phosphogluconate dehydrogenase, nadp, pentose shunt, gluconate utilization |
Biological source | LACTOCOCCUS LACTIS |
Total number of polymer chains | 1 |
Total formula weight | 52914.34 |
Authors | Sundaramoorthy, R.,Iulek, J.,Hunter, W.N. (deposition date: 2006-07-21, release date: 2007-01-23, Last modification date: 2023-12-13) |
Primary citation | Sundaramoorthy, R.,Iulek, J.,Barrett, M.P.,Bidet, O.,Ruda, G.F.,Gilbert, I.H.,Hunter, W.N. Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates. FEBS J., 274:275-, 2007 Cited by PubMed: 17222187DOI: 10.1111/J.1742-4658.2006.05585.X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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