2IT8

Solution structure of a linear analog of the cyclic squash trypsin inhibitor MCoTI-II

Summary for 2IT8

• Entry DOI: 10.2210/pdb2it8/pdb
• Related: 1HA9 1IB9 2C4B 2IT7
• NMR Information: BMRB: 7361
• Descriptor: Trypsin inhibitor 2 (1 entity in total)
• Functional Keywords: plant protein analog, knottin, cystine-knot, 3-10 helix, triple-stranded anti-parallel beta-sheet, plant protein
• Biological source: Momordica cochinchinensis (Spiny bitter cucumber)
• Cellular location: Secreted: P82409
• Total number of polymer chains: 1
• Total formula weight: 3077.70

Authors

Avrutina, O.,Chiche, L.,Diederichsen, U.,Heitz, A.,Kolmar, H. (deposition date: 2006-10-19, release date: 2007-10-02, Last modification date: 2014-04-02)

• Primary citation: Heitz, A.,Avrutina, O.,Le-Nguyen, D.,Diederichsen, U.,Hernandez, J.F.,Gracy, J.,Kolmar, H.,Chiche, L.; Knottin cyclization: Structure and stability of cyclic and linear squash inhibitors do not differ significantly; To be Published,

Experimental method

SOLUTION NMR