2INX
Crystal Structure of Ketosteroid Isomerase D40N from Pseudomonas putida (pKSI) with bound 2,6-difluorophenol
Summary for 2INX
| Entry DOI | 10.2210/pdb2inx/pdb |
| Descriptor | Steroid delta-isomerase, 2,6-DIFLUOROPHENOL (3 entities in total) |
| Functional Keywords | ksi, enzyme, active site, charge distribution, hydrogen bond, isomerase |
| Biological source | Pseudomonas putida |
| Total number of polymer chains | 1 |
| Total formula weight | 14677.61 |
| Authors | Martinez Caaveiro, J.M.,Pybus, B.,Ringe, D.,Petsko, G.A.,Sigala, P.,Kraut, D.,Herschlag, D. (deposition date: 2006-10-09, release date: 2007-10-23, Last modification date: 2023-08-30) |
| Primary citation | Sigala, P.A.,Kraut, D.A.,Caaveiro, J.M.,Pybus, B.,Ruben, E.A.,Ringe, D.,Petsko, G.A.,Herschlag, D. Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole. J.Am.Chem.Soc., 130:13696-13708, 2008 Cited by PubMed: 18808119DOI: 10.1021/ja803928m PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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