2HT8
N8 neuraminidase in complex with oseltamivir
Summary for 2HT8
Entry DOI | 10.2210/pdb2ht8/pdb |
Related | 2H25 2H27 |
Descriptor | Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid (3 entities in total) |
Functional Keywords | n8, neuraminidase, oseltamivir, hydrolase |
Biological source | Influenza A virus |
Cellular location | Virion membrane (By similarity): Q07599 |
Total number of polymer chains | 1 |
Total formula weight | 43441.87 |
Authors | Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J. (deposition date: 2006-07-25, release date: 2006-09-05, Last modification date: 2011-07-13) |
Primary citation | Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature, 443:45-49, 2006 Cited by PubMed: 16915235DOI: 10.1038/nature05114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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