2HJF

Potassium channel kcsa-fab complex with tetrabutylammonium (TBA)

Summary for 2HJF

Entry DOI	10.2210/pdb2hjf/pdb
Descriptor	Antibody fragment Heavy chain, Antibody fragment Light chain, Voltage-gated potassium channel, ... (6 entities in total)
Functional Keywords	potassium channel, ion transport, metal transport
Biological source	Mus musculus (house mouse) More
Cellular location	Cell membrane; Multi-pass membrane protein: P0A334
Total number of polymer chains	3
Total formula weight	58224.57
Authors	Faraldo-Gomez, J.D.,Kutluay, E.,Jogini, V.,Zhao, Y.,Heginbotham, L.,Roux, B. (deposition date: 2006-06-30, release date: 2006-12-05, Last modification date: 2023-08-30)
Primary citation	Faraldo-Gomez, J.D.,Kutluay, E.,Jogini, V.,Zhao, Y.,Heginbotham, L.,Roux, B. Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations. J.Mol.Biol., 365:649-662, 2007 Cited by PubMed: 17070844 DOI: 10.1016/j.jmb.2006.09.069 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation