2HC4
Crystal structure of the LBD of VDR of Danio rerio in complex with calcitriol
Summary for 2HC4
Entry DOI | 10.2210/pdb2hc4/pdb |
Related | 1DB1 2HBH 2HCD |
Descriptor | Vitamin D receptor, SRC-1 from Nuclear receptor coactivator 1, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | alpha helical sandwich, gene regulation |
Biological source | Danio rerio (zebrafish) More |
Cellular location | Nucleus: Q9PTN2 Nucleus (By similarity): Q15788 |
Total number of polymer chains | 2 |
Total formula weight | 36253.38 |
Authors | Ciesielski, F.,Rochel, N.,Moras, D. (deposition date: 2006-06-15, release date: 2007-05-01, Last modification date: 2023-10-25) |
Primary citation | Ciesielski, F.,Rochel, N.,Moras, D. Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation J.Steroid Biochem.Mol.Biol., 103:235-242, 2007 Cited by PubMed: 17218092DOI: 10.1016/j.jsbmb.2006.12.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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