2H9G
Crystal structure of phage derived Fab BdF1 with human Death Receptor 5 (DR5)
Summary for 2H9G
| Entry DOI | 10.2210/pdb2h9g/pdb |
| Related | 1Za3 1d0g |
| Descriptor | Fab BdF1, light chain, Fab BdF1, heavy chain, Tumor necrosis factor receptor superfamily member 10B precursor, ... (4 entities in total) |
| Functional Keywords | phage display, protein engineering, combinatorial mutagenesis, antibody library, death receptor-5, agonists, immune system-apoptosis complex, immune system/apoptosis |
| Biological source | Homo sapiens (human) More |
| Cellular location | Membrane; Single-pass type I membrane protein: O14763 |
| Total number of polymer chains | 6 |
| Total formula weight | 124010.75 |
| Authors | Hymowitz, S.G.,Compaan, D.M. (deposition date: 2006-06-09, release date: 2006-08-08, Last modification date: 2023-08-30) |
| Primary citation | Li, B.,Russell, S.J.,Compaan, D.M.,Totpal, K.,Marsters, S.A.,Ashkenazi, A.,Cochran, A.G.,Hymowitz, S.G.,Sidhu, S.S. Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists. J.Mol.Biol., 361:522-536, 2006 Cited by PubMed: 16859704DOI: 10.1016/j.jmb.2006.06.042 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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