2H7R

L244A mutant of Cytochrome P450cam complexed with imidazole

Summary for 2H7R

Entry DOI	10.2210/pdb2h7r/pdb
Related	1PHC 2CPP 2H7Q 2H7S
Descriptor	Cytochrome P450-cam, PROTOPORPHYRIN IX CONTAINING FE, 1-METHYLIMIDAZOLE, ... (4 entities in total)
Functional Keywords	azole drugs, imidazole binding, cytochrome p450 inhibition, protein maleability, active site conformation, oxidoreductase
Biological source	Pseudomonas putida
Cellular location	Cytoplasm (By similarity): P00183
Total number of polymer chains	1
Total formula weight	47214.34
Authors	Verras, A.,Alian, A.,Montellano, P.R. (deposition date: 2006-06-02, release date: 2006-10-31, Last modification date: 2023-08-30)
Primary citation	Verras, A.,Alian, A.,Montellano, P.R. Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450cam by an L244A mutation. Protein Eng.Des.Sel., 19:491-496, 2006 Cited by PubMed: 16943206 DOI: 10.1093/protein/gzl035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation