2H4N
H94N CARBONIC ANHYDRASE II COMPLEXED WITH ACETAZOLAMIDE
Summary for 2H4N
| Entry DOI | 10.2210/pdb2h4n/pdb |
| Descriptor | CARBONIC ANHYDRASE II, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (4 entities in total) |
| Functional Keywords | lyase, oxo-acid, acetylation |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29486.88 |
| Authors | Lesburg, C.A.,Christianson, D.W. (deposition date: 1997-05-29, release date: 1997-09-17, Last modification date: 2023-08-09) |
| Primary citation | Lesburg, C.A.,Huang, C.,Christianson, D.W.,Fierke, C.A. Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry, 36:15780-15791, 1997 Cited by PubMed: 9398308DOI: 10.1021/bi971296x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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