2H4E

Crystal structure of Cys10 sulfonated transthyretin

Summary for 2H4E

Entry DOI	10.2210/pdb2h4e/pdb
Descriptor	Transthyretin, SULFATE ION (3 entities in total)
Functional Keywords	amyloid, sulfite, transthyretin, familial amyloidotic polyneuropathy, transport protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	27810.91
Authors	Gales, L.,Damas, A.M. (deposition date: 2006-05-24, release date: 2007-01-23, Last modification date: 2023-08-30)
Primary citation	Gales, L.,Saraiva, M.J.,Damas, A.M. Structural basis for the protective role of sulfite against transthyretin amyloid formation. Biochim.Biophys.Acta, 1774:59-64, 2007 Cited by PubMed: 17175208 DOI: 10.1016/j.bbapap.2006.10.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation