2H43

Crystal Structure of Human Fragment D Complexed with Ala-His-Arg-Pro-amide

Summary for 2H43

• Entry DOI: 10.2210/pdb2h43/pdb
• Related: 1FZG
• Descriptor: Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, ... (7 entities in total)
• Functional Keywords: knob-hole interaction, fragment d, coiled-coil, blood clotting
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 171051.43

Authors

Doolittle, R.F.,Pandi, L. (deposition date: 2006-05-23, release date: 2006-12-05, Last modification date: 2020-07-29)

• Primary citation: Doolittle, R.F.,Chen, A.,Pandi, L.; Differences in Binding Specificity for the Homologous gamma- and beta-Chain "Holes" on Fibrinogen: Exclusive Binding of Ala-His-Arg-Pro-amide by the beta-Chain Hole.; Biochemistry, 45:13962-13969, 2006; PubMed: 17115691; DOI: 10.1021/bi061219e

Experimental method

X-RAY DIFFRACTION (2.7 Å)