2EKS

Crystal structure of humanized HyHEL-10 FV-HEN lysozyme complex

Summary for 2EKS

• Entry DOI: 10.2210/pdb2eks/pdb
• Related: 2EIZ
• Descriptor: ANTI-LYSOZYME ANTIBODY FV REGION, Lysozyme C, ... (4 entities in total)
• Functional Keywords: immune system, hydrolase, immune system-hydrolase complex, immune system/hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 3
• Total formula weight: 38469.93

Authors

Nakanishi, T.,Tsumoto, K.,Yokota, A.,Kondo, H.,Kumagai, I. (deposition date: 2007-03-24, release date: 2008-03-25, Last modification date: 2023-10-25)

• Primary citation: Nakanishi, T.,Tsumoto, K.,Yokota, A.,Kondo, H.,Kumagai, I.; Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10; Protein Sci., 17:261-270, 2008; PubMed: 18227432; DOI: 10.1110/ps.073156708

Experimental method

X-RAY DIFFRACTION (2 Å)