2DY5
Crystal structure of rat heme oxygenase-1 in complex with heme and 2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolane
Summary for 2DY5
| Entry DOI | 10.2210/pdb2dy5/pdb |
| Descriptor | Heme oxygenase 1, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
| Functional Keywords | inhibitor, substrate bound structure, oxidoreductase |
| Biological source | Rattus norvegicus (Norway rat) |
| Cellular location | Microsome: P06762 |
| Total number of polymer chains | 1 |
| Total formula weight | 31557.20 |
| Authors | Sugishima, M.,Takahashi, H.,Fukuyama, K. (deposition date: 2006-09-06, release date: 2007-05-22, Last modification date: 2023-10-25) |
| Primary citation | Sugishima, M.,Higashimoto, Y.,Oishi, T.,Takahashi, H.,Sakamoto, H.,Noguchi, M.,Fukuyama, K. X-ray crystallographic and biochemical characterization of the inhibitory action of an imidazole-dioxolane compound on heme oxygenase Biochemistry, 46:1860-1867, 2007 Cited by PubMed: 17253780DOI: 10.1021/bi062264p PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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