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2D1X

The crystal structure of the cortactin-SH3 domain and AMAP1-peptide complex

Summary for 2D1X
Entry DOI10.2210/pdb2d1x/pdb
Descriptorcortactin isoform a, proline rich region from development and differentiation enhancing factor 1, SULFATE ION, ... (4 entities in total)
Functional Keywordssh3, proline-rich, complex, cell invasion
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm, cytoskeleton: Q14247
Total number of polymer chains6
Total formula weight32944.26
Authors
Primary citationHashimoto, S.,Hirose, M.,Hashimoto, A.,Morishige, M.,Yamada, A.,Hosaka, H.,Akagi, K.,Ogawa, E.,Oneyama, C.,Agatsuma, T.,Okada, M.,Kobayashi, H.,Wada, H.,Nakano, H.,Ikegami, T.,Nakagawa, A.,Sabe, H.
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Proc.Natl.Acad.Sci.Usa, 103:7036-7041, 2006
Cited by
PubMed: 16636290
DOI: 10.1073/pnas.0509166103
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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