2C7O

HhaI DNA methyltransferase complex with 13mer oligonucleotide containing 2-aminopurine adjacent to the target base (PCGC:GMGC) and SAH

Summary for 2C7O

• Entry DOI: 10.2210/pdb2c7o/pdb
• Related: 10MH 1FJX 1HMY 1M0E 1MHT 1SKM 1SVU 2C7P 2C7Q 2C7R 2HMY 3MHT 4MHT 5MHT 6MHT 7MHT 8MHT 9MHT
• Descriptor: MODIFICATION METHYLASE HHAI, 5'-D(*T*GP*GP*AP*TP*GP*(5CM)*GP*CP*TP*GP*AP *C)-3', 5'-D(*T*GP*TP*CP*AP*(2PR)*CP*GP*CP*AP*TP*CP *C)-3', ... (6 entities in total)
• Functional Keywords: transferase-dna complex, base flipping, transferase restriction system, transferase/dna
• Biological source: HAEMOPHILUS HAEMOLYTICUS; More
• Total number of polymer chains: 3
• Total formula weight: 45744.07

Authors

Daujotyte, D.,Grazulis, S. (deposition date: 2005-11-25, release date: 2005-12-14, Last modification date: 2023-12-13)

• Primary citation: Neely, R.K.,Daujotyte, D.,Grazulis, S.,Magennis, S.W.,Dryden, D.T.F.,Klimasauskas, S.,Jones, A.C.; Time-Resolved Fluorescence of 2-Aminopurine as a Probe of Base Flipping in M.HhaI-DNA Complexes.; Nucleic Acids Res., 33:6953-, 2005; PubMed: 16340006; DOI: 10.1093/NAR/GKI995

Experimental method

X-RAY DIFFRACTION (1.9 Å)