2C62

Crystal Structure of the Human Transcription Cofactor PC4 in Complex with Single-Stranded DNA

Summary for 2C62

• Entry DOI: 10.2210/pdb2c62/pdb
• Related: 1PCF
• Descriptor: ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15, 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*TP*TP*TP*TP*G)-3', SULFATE ION, ... (4 entities in total)
• Functional Keywords: transcription cofactor, single-stranded dna, protein-dna complex, dna unwinding, activator, dna-binding, nuclear protein, phosphorylation, transcription, transcription regulation
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus: P53999
• Total number of polymer chains: 3
• Total formula weight: 21824.09

Authors

Werten, S.,Moras, D. (deposition date: 2005-11-07, release date: 2006-01-11, Last modification date: 2023-12-13)

• Primary citation: Werten, S.,Moras, D.; A Global Transcription Cofactor Bound to Juxtaposed Strands of Unwound DNA; Nat.Struct.Mol.Biol., 13:181-, 2006; PubMed: 16415882; DOI: 10.1038/NSMB1044

Experimental method

X-RAY DIFFRACTION (1.74 Å)