2BFZ
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Summary for 2BFZ
Entry DOI | 10.2210/pdb2bfz/pdb |
Related | 2BG2 2BG6 2BG7 2BG8 2BGA |
Descriptor | BETA-LACTAMASE II, GLYCEROL, ZINC ION, ... (7 entities in total) |
Functional Keywords | hydrolase, antibiotic resistance |
Biological source | BACILLUS CEREUS More |
Total number of polymer chains | 2 |
Total formula weight | 51509.02 |
Authors | Davies, A.M.,Rasia, R.M.,Vila, A.J.,Sutton, B.J.,Fabiane, S.M. (deposition date: 2004-12-16, release date: 2005-03-31, Last modification date: 2023-12-13) |
Primary citation | Davies, A.M.,Rasia, R.M.,Vila, A.J.,Sutton, B.J.,Fabiane, S.M. Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism Biochemistry, 44:4841-, 2005 Cited by PubMed: 15779910DOI: 10.1021/BI047709T PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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