2AM2
sp protein ligand 2
Summary for 2AM2
Entry DOI | 10.2210/pdb2am2/pdb |
Related | 2AM1 |
Descriptor | UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, MurF protein, 2-CHLORO-N-(3-CYANO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-2-YL)-5-DIETHYLSULFAMOYL-BENZAMIDE (3 entities in total) |
Functional Keywords | ligase |
Biological source | Streptococcus pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 51184.57 |
Authors | Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R. (deposition date: 2005-08-08, release date: 2006-01-24, Last modification date: 2023-11-15) |
Primary citation | Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R.,Holzman, T.F.,Gu, Y.G.,Lerner, C.G.,Beutel, B.A.,Stoll, V.S. Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure Protein Sci., 14:3039-3047, 2005 Cited by PubMed: 16322581DOI: 10.1110/ps.051604805 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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