29AK

Crystal structure of PaLpxC complexed with compound 8k

This is a non-PDB format compatible entry.

Summary for 29AK

• Entry DOI: 10.2210/pdb29ak/pdb
• Descriptor: UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, 4-[(2S)-3-[[(2S)-1-fluoranylpropan-2-yl]amino]-2-[4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]phenyl]propyl]-5-oxidanyl-1H-pyrimidin-6-one, ... (5 entities in total)
• Functional Keywords: lpxc, metalloprotease, antibiotic, inhibitor
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 1
• Total formula weight: 33927.84

Authors

Beaumont, E.,Cade, I.,Kopec, J.,Martin, D. (deposition date: 2026-03-03, release date: 2026-07-29)

• Primary citation: Beaumont, E.,Cade, I.,Kopec, J.,Martin, D.; Crystal structure of PaLpxC complexed with compound 8k; To Be Published, 2026; DOI: 10.1021/acs.jmedchem.6c01036

Experimental method

X-RAY DIFFRACTION (1.504 Å)