280D

THE STRUCTURE OF AN RNA DODECAMER SHOWS HOW TANDEM U-U BASE PAIRS INCREASE THE RANGE OF STABLE RNA STRUCTURES AND THE DIVERSITY OF RECOGNITION SITES

280D の概要

• エントリーDOI: 10.2210/pdb280d/pdb
• 分子名称: RNA (5'-R(*GP*GP*CP*GP*CP*UP*UP*GP*CP*GP*UP*C)-3') (2 entities in total)
• 機能のキーワード: unusual rna, double helix, internal loop, mismatched, rna
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 15281.18

構造登録者

Lietzke, S.E.,Barnes, C.L.,Kundrot, C.E. (登録日: 1996-08-22, 公開日: 1996-09-30, 最終更新日: 2024-04-03)

主引用文献

Lietzke, S.E.,Barnes, C.L.,Berglund, J.A.,Kundrot, C.E.
The structure of an RNA dodecamer shows how tandem U-U base pairs increase the range of stable RNA structures and the diversity of recognition sites.
Structure, 4:917-930, 1996

PubMed Abstract: Non-canonical base pairs are fundamental building blocks of RNA structures. They can adopt geometries quite different from those of canonical base pairs and are common in RNA molecules that do not transfer sequence information. Tandem U-U base pairs occur frequently, and can stabilize duplex formation despite the fact that a single U-U base pair is destabilizing.

PubMed: 8805576
DOI: 10.1016/S0969-2126(96)00099-8

実験手法

X-RAY DIFFRACTION (2.4 Å)