236D
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Summary for 236D
Entry DOI | 10.2210/pdb236d/pdb |
Descriptor | DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), 3'-DESAMINO-3'-(3-CYANO-4-MORPHOLINYL)-DOXORUBICIN (3 entities in total) |
Functional Keywords | right handed dna, double helix, complexed with drug, dna |
Total number of polymer chains | 1 |
Total formula weight | 2447.84 |
Authors | Gao, Y.-G.,Wang, A.H.-J. (deposition date: 1995-06-22, release date: 1996-01-31, Last modification date: 2024-02-14) |
Primary citation | Gao, Y.G.,Wang, A.H. Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink. J.Biomol.Struct.Dyn., 13:103-117, 1995 Cited by PubMed: 8527023PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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