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22GS

HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y49F MUTANT

Summary for 22GS
Entry DOI10.2210/pdb22gs/pdb
DescriptorGLUTATHIONE S-TRANSFERASE P1-1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total)
Functional Keywordstransferase, glutathione, pi, detoxification, y49f
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P09211
Total number of polymer chains2
Total formula weight47309.25
Authors
Oakley, A.J. (deposition date: 1998-03-10, release date: 1999-03-23, Last modification date: 2023-08-09)
Primary citationOrtiz-Salmeron, E.,Nuccetelli, M.,Oakley, A.J.,Parker, M.W.,Lo Bello, M.,Garcia-Fuentes, L.
Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione.
J.Biol.Chem., 278:46938-46948, 2003
Cited by
PubMed: 12937169
DOI: 10.1074/jbc.M305043200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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