227D
A CRYSTALLOGRAPHIC AND SPECTROSCOPIC STUDY OF THE COMPLEX BETWEEN D(CGCGAATTCGCG)2 AND 2,5-BIS(4-GUANYLPHENYL)FURAN, AN ANALOGUE OF BERENIL. STRUCTURAL ORIGINS OF ENHANCED DNA-BINDING AFFINITY
Summary for 227D
Entry DOI | 10.2210/pdb227d/pdb |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2,5-BIS(4-GUANYLPHENYL)FURAN (3 entities in total) |
Functional Keywords | b-dna, double helix, complexed with drug, dna |
Total number of polymer chains | 2 |
Total formula weight | 7633.15 |
Authors | Laughton, C.A.,Tanious, F.,Nunn, C.M.,Boykin, D.W.,Wilson, W.D.,Neidle, S. (deposition date: 1995-08-08, release date: 1995-11-11, Last modification date: 2024-02-14) |
Primary citation | Laughton, C.A.,Tanious, F.,Nunn, C.M.,Boykin, D.W.,Wilson, W.D.,Neidle, S. A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity. Biochemistry, 35:5655-5661, 1996 Cited by PubMed: 8639524DOI: 10.1021/bi952162r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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