Bovine eNOS N368D/V106M double mutant with L-N(omega)-Nitroarginine-(4R)-Amino-L-Proline Amide Bound

Summary for 1ZZT

DescriptorNitric-oxide synthase, endothelial, ACETATE ION, ZINC ION, ... (7 entities in total)
Functional Keywordsenzyme-inhibtor complex, oxidoreductase
Biological sourceBos taurus (cattle)
Cellular locationCell membrane P29473
Total number of polymer chains2
Total molecular weight96541.77
Li, H.,Flinspach, M.L.,Igarashi, J.,Jamal, J.,Yang, W.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2005-06-14, release date: 2005-12-06, Last modification date: 2011-07-13)
Primary citation
Li, H.,Flinspach, M.L.,Igarashi, J.,Jamal, J.,Yang, W.,Litzinger, E.A.,Huang, H.,Erdal, E.P.,Silverman, R.B.,Poulos, T.L.
Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44:15222-15229, 2005
PubMed: 16285725 (PDB entries with the same primary citation)
DOI: 10.1021/bi0513610
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22491.0%2.0%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution