1ZZQ

Rat nNOS D597N mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide bound

Summary for 1ZZQ

Related1P6J
DescriptorNitric-oxide synthase, brain, ACETATE ION, ZINC ION, ... (8 entities in total)
Functional Keywordsoxydoreductase enzyme-inhibitor complex, oxidoreductase
Biological sourceRattus norvegicus (Norway rat)
Cellular locationCell membrane, sarcolemma; Peripheral membrane protein (By similarity) P29476
Total number of polymer chains2
Total molecular weight100146.56
Authors
Li, H.,Flinspach, M.L.,Igarashi, J.,Jamal, J.,Yang, W.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2005-06-14, release date: 2005-12-06, Last modification date: 2011-07-13)
Primary citation
Li, H.,Flinspach, M.L.,Igarashi, J.,Jamal, J.,Yang, W.,Litzinger, E.A.,Huang, H.,Erdal, E.P.,Silverman, R.B.,Poulos, T.L.
Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44:15222-15229, 2005
PubMed: 16285725 (PDB entries with the same primary citation)
DOI: 10.1021/bi0513610
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.236801.6%8.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report