1ZX1

Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954

1ZX1 の概要

• エントリーDOI: 10.2210/pdb1zx1/pdb
• 関連するPDBエントリー: 1QR1 1QR2
• 分子名称: NRH dehydrogenase [quinone] 2, ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• 機能のキーワード: quinone oxidoreductase 2, reductions of quinones, dihydronicotinamide ribose, electrondonor, 5-(aziridin-1-yl)-2, 4-dinitrobenamide (cb1954), flavin-containing, structural genomics, structural genomics consortium, sgc, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54167.35

構造登録者

Jansson, A.,Wu, X.,Kavanagh, K.,Kerr, D.,Knox, R.,Walton, R.,Gunther, U.,Ludwig, C.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Oppermann, U.,Structural Genomics Consortium (SGC) (登録日: 2005-06-06, 公開日: 2005-06-14, 最終更新日: 2023-08-23)

• 主引用文献: Jansson, A.,Wu, X.,Kavanagh, K.,Kerr, D.,Knox, R.,Walton, R.,Gunther, U.,Ludwig, C.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Oppermann, U.; Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954; To be Published,

実験手法

X-RAY DIFFRACTION (2.16 Å)