1ZW5
X-ray structure of Farnesyl diphosphate synthase protein
Summary for 1ZW5
Entry DOI | 10.2210/pdb1zw5/pdb |
Related | 1YV5 |
Descriptor | farnesyl diphosphate synthase, MAGNESIUM ION, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | isoprenoid pathway, cholesterol synthesis, bisphosphonate, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P14324 |
Total number of polymer chains | 1 |
Total formula weight | 41361.55 |
Authors | Kavanagh, K.L.,Guo, K.,Wu, X.,von Delft, F.,Arrowsmith, C.,Sundstrom, M.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2005-06-03, release date: 2005-06-28, Last modification date: 2023-08-23) |
Primary citation | Kavanagh, K.L.,Guo, K.,Dunford, J.E.,Wu, X.,Knapp, S.,Ebetino, F.H.,Rogers, M.J.,Russell, R.G.,Oppermann, U. The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc.Natl.Acad.Sci.USA, 103:7829-7834, 2006 Cited by PubMed: 16684881DOI: 10.1073/pnas.0601643103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report