1ZV4

Structure of the Regulator of G-Protein Signaling 17 (RGSZ2)

Summary for 1ZV4

• Entry DOI: 10.2210/pdb1zv4/pdb
• Descriptor: Regulator of G-protein signaling 17 (2 entities in total)
• Functional Keywords: human rgsz2, human rgs17(z2); regulator of g-protein signaling; mu-opioid receptor interacting protein, gtpase-activating proteins (gap), regulator of gz-selective protein signaling 2, structural genomics, structural genomics consortium, sgc, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Lipid-anchor: Q9UGC6
• Total number of polymer chains: 1
• Total formula weight: 18727.10

Authors

Schoch, G.A.,Jansson, A.,Elkins, J.M.,Haroniti, A.,Niesen, F.H.,Bunkoczi, G.,Lee, W.H.,Turnbull, A.P.,Yang, X.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Marsden, B.,Gileadi, O.,Ball, L.,von Delft, F.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2005-06-01, release date: 2005-06-28, Last modification date: 2023-08-23)

• Primary citation: Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.; Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.; Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008; PubMed: 18434541; DOI: 10.1073/pnas.0801508105

Experimental method

X-RAY DIFFRACTION (2.4 Å)