1ZSQ

Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate

Summary for 1ZSQ

Entry DOI	10.2210/pdb1zsq/pdb
Descriptor	Myotubularin-related protein 2, 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, ... (4 entities in total)
Functional Keywords	protein-phospholipid complex, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q13614
Total number of polymer chains	1
Total formula weight	61907.05
Authors	Begley, M.J.,Taylor, G.S.,Brock, M.A.,Ghosh, P.,Woods, V.L.,Dixon, J.E. (deposition date: 2005-05-25, release date: 2006-01-31, Last modification date: 2023-08-23)
Primary citation	Begley, M.J.,Taylor, G.S.,Brock, M.A.,Ghosh, P.,Woods, V.L.,Dixon, J.E. Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase Proc.Natl.Acad.Sci.Usa, 103:927-932, 2006 Cited by PubMed: 16410353 DOI: 10.1073/pnas.0510006103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation