1ZSQ

Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate

1ZSQ の概要

• エントリーDOI: 10.2210/pdb1zsq/pdb
• 分子名称: Myotubularin-related protein 2, 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, ... (4 entities in total)
• 機能のキーワード: protein-phospholipid complex, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q13614
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61907.05

構造登録者

Begley, M.J.,Taylor, G.S.,Brock, M.A.,Ghosh, P.,Woods, V.L.,Dixon, J.E. (登録日: 2005-05-25, 公開日: 2006-01-31, 最終更新日: 2023-08-23)

• 主引用文献: Begley, M.J.,Taylor, G.S.,Brock, M.A.,Ghosh, P.,Woods, V.L.,Dixon, J.E.; Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase; Proc.Natl.Acad.Sci.Usa, 103:927-932, 2006; PubMed: 16410353; DOI: 10.1073/pnas.0510006103

実験手法

X-RAY DIFFRACTION (1.82 Å)