1ZP5

Crystal structure of the complex between MMP-8 and a N-hydroxyurea inhibitor

Summary for 1ZP5

Entry DOI	10.2210/pdb1zp5/pdb
Descriptor	Neutrophil collagenase, CALCIUM ION, ZINC ION, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasmic granule: P22894
Total number of polymer chains	1
Total formula weight	18634.05
Authors	Campestre, C.,Agamennone, M.,Tortorella, P.,Preziuso, S.,Biasone, A.,Gavuzzo, E.,Pochetti, G.,Mazza, F.,Tschesche, H.,Gallina, C. (deposition date: 2005-05-16, release date: 2005-12-06, Last modification date: 2023-08-23)
Primary citation	Campestre, C.,Agamennone, M.,Tortorella, P.,Preziuso, S.,Biasone, A.,Gavuzzo, E.,Pochetti, G.,Mazza, F.,Hiller, O.,Tschesche, H.,Consalvi, V.,Gallina, C. N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: Mode of binding in a complex with MMP-8. Bioorg.Med.Chem.Lett., 16:20-24, 2006 Cited by PubMed: 16242329 DOI: 10.1016/j.bmcl.2005.09.057 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation