1ZMI

Crystal structure of human alpha_defensin-2 (variant GLY16->D-ALA), P 32 2 1 space group )

Summary for 1ZMI

Entry DOI	10.2210/pdb1zmi/pdb
Related	1DFN 1ZMH 1ZMK 1ZMM 1ZMP 1ZMQ
Descriptor	Neutrophil defensin 2, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywords	alpha-defensin, antimicrobial, d-amino acid substitution, antimicrobial protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P59666
Total number of polymer chains	4
Total formula weight	14236.80
Authors	Lubkowski, J.,Prahl, A.,Lu, W. (deposition date: 2005-05-10, release date: 2005-08-16, Last modification date: 2023-08-23)
Primary citation	Xie, C.,Prahl, A.,Ericksen, B.,Wu, Z.,Zeng, P.,Li, X.,Lu, W.Y.,Lubkowski, J.,Lu, W. Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids. J.Biol.Chem., 280:32921-32929, 2005 Cited by PubMed: 15894545 DOI: 10.1074/jbc.M503084200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.15 Å)

Structure validation