1ZLH

Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A

1ZLH の概要

• エントリーDOI: 10.2210/pdb1zlh/pdb
• 関連するPDBエントリー: 1ZLI
• 分子名称: Carboxypeptidase A1, carboxypeptidase inhibitor, ZINC ION, ... (4 entities in total)
• 機能のキーワード: inhibitor-metallocarboxypeptidase complex, beta-defensin fold (tci), eight-stranded twisted beta-sheet surrounded by eight alpha-helices (cpa), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Secreted, extracellular space: P00730
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 42993.90

構造登録者

Arolas, J.L.,Popowicz, G.M.,Lorenzo, J.,Sommerhoff, C.P.,Huber, R.,Aviles, F.X.,Holak, T.A. (登録日: 2005-05-06, 公開日: 2005-07-05, 最終更新日: 2017-10-11)

• 主引用文献: Arolas, J.L.,Popowicz, G.M.,Lorenzo, J.,Sommerhoff, C.P.,Huber, R.,Aviles, F.X.,Holak, T.A.; The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode; J.Mol.Biol., 350:489-498, 2005; PubMed: 15961103; DOI: 10.1016/j.jmb.2005.05.015

実験手法

X-RAY DIFFRACTION (1.7 Å)