1ZJK

Crystal structure of the zymogen catalytic region of human MASP-2

Summary for 1ZJK

Entry DOI	10.2210/pdb1zjk/pdb
Descriptor	Mannan-binding lectin serine protease 2 (2 entities in total)
Functional Keywords	beta barrel, modular protein, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted: O00187
Total number of polymer chains	1
Total formula weight	44031.71
Authors	Gal, P.,Harmat, V.,Kocsis, A.,Bian, T.,Barna, L.,Ambrus, G.,Vegh, B.,Balczer, J.,Sim, R.B.,Naray-Szabo, G.,Zavodszky, P. (deposition date: 2005-04-29, release date: 2005-07-26, Last modification date: 2023-08-23)
Primary citation	Gal, P.,Harmat, V.,Kocsis, A.,Bian, T.,Barna, L.,Ambrus, G.,Vegh, B.,Balczer, J.,Sim, R.B.,Naray-Szabo, G.,Zavodszky, P. A True Autoactivating Enzyme: Structural insight into mannose-binding lectin-associated serine protease-2 activations J.Biol.Chem., 280:33435-33444, 2005 Cited by PubMed: 16040602 DOI: 10.1074/jbc.M506051200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation