1ZID

LONG FATTY ACID CHAIN ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH AN ISONICOTINIC-ACYL-NADH INHIBITOR

1ZID の概要

• エントリーDOI: 10.2210/pdb1zid/pdb
• 分子名称: ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: oxidoreductase, inha enzyme, isoniazid, modified nadh, enoyl-acp reductase, tuberculosis, mycolic acid biosynthesis, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29162.08

構造登録者

Rozwarski, D.A.,Jacobs Jr., W.R.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 1997-03-25, 公開日: 1998-03-25, 最終更新日: 2024-05-22)

• 主引用文献: Rozwarski, D.A.,Grant, G.A.,Barton, D.H.,Jacobs Jr., W.R.,Sacchettini, J.C.; Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis.; Science, 279:98-102, 1998; PubMed: 9417034; DOI: 10.1126/science.279.5347.98

実験手法

X-RAY DIFFRACTION (2.7 Å)