1ZGY

Structural and Biochemical Basis for Selective Repression of the Orphan Nuclear Receptor LRH-1 by SHP

1ZGY の概要

• エントリーDOI: 10.2210/pdb1zgy/pdb
• 分子名称: Peroxisome proliferator activated receptor gamma, Nuclear receptor subfamily 0, group B, member 2, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... (4 entities in total)
• 機能のキーワード: protein-peptide complex, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P37231; Cytoplasm : P97947
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33301.76

構造登録者

Li, Y.,Choi, M.,Suino, K.,Kovach, A.,Daugherty, J.,Kliewer, S.A.,Xu, H.E. (登録日: 2005-04-22, 公開日: 2005-07-26, 最終更新日: 2023-08-23)

• 主引用文献: Li, Y.,Choi, M.,Suino, K.,Kovach, A.,Daugherty, J.,Kliewer, S.A.,Xu, H.E.; Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner.; Proc.Natl.Acad.Sci.Usa, 102:9505-9510, 2005; PubMed: 15976031; DOI: 10.1073/pnas.0501204102

実験手法

X-RAY DIFFRACTION (1.8 Å)